Enzyme Replacement Therapy Market Research Report by Therapeutic Condition, Route of Administration, Enzyme Type, End-User, Region - Global Forecast to 2027 - Cumulative Impact of COVID-19

The Global Enzyme Replacement Therapy Market size was estimated at USD 6,738.37 million in 2021 and expected to reach USD 7,379.86 million in 2022, and is projected to grow at a CAGR 9.69% to reach USD 11,741.52 million by 2027.

Market Statistics:
The report provides market sizing and forecast across 7 major currencies - USD, EUR, JPY, GBP, AUD, CAD, and CHF. It helps organization leaders make better decisions when currency exchange data is readily available. In this report, the years 2018 and 2020 are considered as historical years, 2021 as the base year, 2022 as the estimated year, and years from 2023 to 2027 are considered as the forecast period.

Market Segmentation & Coverage:
This research report categorizes the Enzyme Replacement Therapy to forecast the revenues and analyze the trends in each of the following sub-markets:

Based on Therapeutic Condition, the market was studied across Fabry Disease, Gaucher Disease, MPS, Pompe Disease, and SCID. The MPS is further studied across MPS I - Hurler, Hurler Scheie and Scheie, MPS II - Hunter, and MPS III - Sanfilippo.

Based on Route of Administration, the market was studied across Oral and Parenteral.

Based on Enzyme Type, the market was studied across Agalsidase Beta, Alglucosidase Alfa, Galsulfase, Idursulfase, Imiglucerase, Laronidase, Pancreatic Enzymes, Pegademase, Taliglucerase, and Velaglucerase Alfa.

Based on End-User, the market was studied across Hospitals and Infusion Centers.

Based on Region, the market was studied across Americas, Asia-Pacific, and Europe, Middle East & Africa. The Americas is further studied across Argentina, Brazil, Canada, Mexico, and United States. The United States is further studied across California, Florida, Illinois, New York, Ohio, Pennsylvania, and Texas. The Asia-Pacific is further studied across Australia, China, India, Indonesia, Japan, Malaysia, Philippines, Singapore, South Korea, Taiwan, Thailand, and Vietnam. The Europe, Middle East & Africa is further studied across Denmark, Egypt, Finland, France, Germany, Israel, Italy, Netherlands, Nigeria, Norway, Poland, Qatar, Russia, Saudi Arabia, South Africa, Spain, Sweden, Switzerland, Turkey, United Arab Emirates, and United Kingdom.

Cumulative Impact of COVID-19:
COVID-19 is an incomparable global public health emergency that has affected almost every industry, and the long-term effects are projected to impact the industry growth during the forecast period. Our ongoing research amplifies our research framework to ensure the inclusion of underlying COVID-19 issues and potential paths forward. The report delivers insights on COVID-19 considering the changes in consumer behavior and demand, purchasing patterns, re-routing of the supply chain, dynamics of current market forces, and the significant interventions of governments. The updated study provides insights, analysis, estimations, and forecasts, considering the COVID-19 impact on the market.

Cumulative Impact of 2022 Russia Ukraine Conflict:
We continuously monitor and update reports on political and economic uncertainty due to the Russian invasion of Ukraine. Negative impacts are significantly foreseen globally, especially across Eastern Europe, European Union, Eastern & Central Asia, and the United States. This contention has severely affected lives and livelihoods and represents far-reaching disruptions in trade dynamics. The potential effects of ongoing war and uncertainty in Eastern Europe are expected to have an adverse impact on the world economy, with especially long-term harsh effects on Russia.This report uncovers the impact of demand & supply, pricing variants, strategic uptake of vendors, and recommendations for Enzyme Replacement Therapy market considering the current update on the conflict and its global response.

Competitive Strategic Window:
The Competitive Strategic Window analyses the competitive landscape in terms of markets, applications, and geographies to help the vendor define an alignment or fit between their capabilities and opportunities for future growth prospects. It describes the optimal or favorable fit for the vendors to adopt successive merger and acquisition strategies, geography expansion, research & development, and new product introduction strategies to execute further business expansion and growth during a forecast period.

FPNV Positioning Matrix:
The FPNV Positioning Matrix evaluates and categorizes the vendors in the Enzyme Replacement Therapy Market based on Business Strategy (Business Growth, Industry Coverage, Financial Viability, and Channel Support) and Product Satisfaction (Value for Money, Ease of Use, Product Features, and Customer Support) that aids businesses in better decision making and understanding the competitive landscape.

Market Share Analysis:
The Market Share Analysis offers the analysis of vendors considering their contribution to the overall market. It provides the idea of its revenue generation into the overall market compared to other vendors in the space. It provides insights into how vendors are performing in terms of revenue generation and customer base compared to others. Knowing market share offers an idea of the size and competitiveness of the vendors for the base year. It reveals the market characteristics in terms of accumulation, fragmentation, dominance, and amalgamation traits.

Competitive Scenario:
The Competitive Scenario provides an outlook analysis of the various business growth strategies adopted by the vendors. The news covered in this section deliver valuable thoughts at the different stage while keeping up-to-date with the business and engage stakeholders in the economic debate. The competitive scenario represents press releases or news of the companies categorized into Merger & Acquisition, Agreement, Collaboration, & Partnership, New Product Launch & Enhancement, Investment & Funding, and Award, Recognition, & Expansion. All the news collected help vendor to understand the gaps in the marketplace and competitor’s strength and weakness thereby, providing insights to enhance product and service.

Company Usability Profiles:
The report profoundly explores the recent significant developments by the leading vendors and innovation profiles in the Global Enzyme Replacement Therapy Market, including Abbott Laboratories, AbbVie Inc., Actelion, Alexion Pharmaceuticals Inc., Allergan plc, Amicus Therapeutics, BioMarin Pharmaceutical Inc., CANBridge Pharmaceuticals, Clinigen Group, Generium, Horizon Pharma Public Limited Company, Intouch Pharmacy, Menarini, MLD Foundation, Pfizer Inc., Protalix Biotherapeutics, Recordati Rare Diseases., Sanofi S.A., Shire Plc, Sigma Aldrich, Sigma-Tau Pharmaceuticals Inc., Takeda Pharmaceutical Company Ltd, and Teijin Pharma Ltd.

The report provides insights on the following pointers:
1. Market Penetration: Provides comprehensive information on the market offered by the key players
2. Market Development: Provides in-depth information about lucrative emerging markets and analyze penetration across mature segments of the markets
3. Market Diversification: Provides detailed information about new product launches, untapped geographies, recent developments, and investments
4. Competitive Assessment & Intelligence: Provides an exhaustive assessment of market shares, strategies, products, certification, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players
5. Product Development & Innovation: Provides intelligent insights on future technologies, R&D activities, and breakthrough product developments

The report answers questions such as:
1. What is the market size and forecast of the Global Enzyme Replacement Therapy Market?
2. What are the inhibiting factors and impact of COVID-19 shaping the Global Enzyme Replacement Therapy Market during the forecast period?
3. Which are the products/segments/applications/areas to invest in over the forecast period in the Global Enzyme Replacement Therapy Market?
4. What is the competitive strategic window for opportunities in the Global Enzyme Replacement Therapy Market?
5. What are the technology trends and regulatory frameworks in the Global Enzyme Replacement Therapy Market?
6. What is the market share of the leading vendors in the Global Enzyme Replacement Therapy Market?
7. What modes and strategic moves are considered suitable for entering the Global Enzyme Replacement Therapy Market?

1. Preface
1.1. Objectives of the Study
1.2. Market Segmentation & Coverage
1.3. Years Considered for the Study
1.4. Currency & Pricing
1.5. Language
1.6. Limitations
1.7. Assumptions
1.8. Stakeholders

2. Research Methodology
2.1. Define: Research Objective
2.2. Determine: Research Design
2.3. Prepare: Research Instrument
2.4. Collect: Data Source
2.5. Analyze: Data Interpretation
2.6. Formulate: Data Verification
2.7. Publish: Research Report
2.8. Repeat: Report Update

3. Executive Summary

4. Market Overview

5. Market Insights
5.1. Market Dynamics
5.1.1. Drivers
5.1.1.1. Increasing awareness about rare diseases
5.1.1.2. Availability of enzyme therapy with ease of guidelines for the approval purpose
5.1.1.3. Government support in treatment initiatives
5.1.2. Restraints
5.1.2.1. High cost and side effects of the treatment
5.1.3. Opportunities
5.1.3.1. Advent of orphan disease management
5.1.3.2. High investments in R&D to treat rare diseases
5.1.4. Challenges
5.1.4.1. Low prevalence of rare or orphan diseases
5.2. Cumulative Impact of COVID-19

6. Enzyme Replacement Therapy Market, by Therapeutic Condition
6.1. Introduction
6.2. Fabry Disease
6.3. Gaucher Disease
6.4. MPS
6.5.1. MPS I - Hurler, Hurler Scheie and Scheie
6.5.2. MPS II - Hunter
6.5.3. MPS III - Sanfilippo
6.5. Pompe Disease
6.6. SCID

7. Enzyme Replacement Therapy Market, by Route of Administration
7.1. Introduction
7.2. Oral
7.3. Parenteral

8. Enzyme Replacement Therapy Market, by Enzyme Type
8.1. Introduction
8.2. Agalsidase Beta
8.3. Alglucosidase Alfa
8.4. Galsulfase
8.5. Idursulfase
8.6. Imiglucerase
8.7. Laronidase
8.8. Pancreatic Enzymes
8.9. Pegademase
8.10. Taliglucerase
8.11. Velaglucerase Alfa

9. Enzyme Replacement Therapy Market, by End-User
9.1. Introduction
9.2. Hospitals
9.3. Infusion Centers

10. Americas Enzyme Replacement Therapy Market
10.1. Introduction
10.2. Argentina
10.3. Brazil
10.4. Canada
10.5. Mexico
10.6. United States

11. Asia-Pacific Enzyme Replacement Therapy Market
11.1. Introduction
11.2. Australia
11.3. China
11.4. India
11.5. Indonesia
11.6. Japan
11.7. Malaysia
11.8. Philippines
11.9. Singapore
11.10. South Korea
11.11. Taiwan
11.12. Thailand
11.13. Vietnam

12. Europe, Middle East & Africa Enzyme Replacement Therapy Market
12.1. Introduction
12.2. Denmark
12.3. Egypt
12.4. Finland
12.5. France
12.6. Germany
12.7. Israel
12.8. Italy
12.9. Netherlands
12.10. Nigeria
12.11. Norway
12.12. Poland
12.13. Qatar
12.14. Russia
12.15. Saudi Arabia
12.16. South Africa
12.17. Spain
12.18. Sweden
12.19. Switzerland
12.20. Turkey
12.21. United Arab Emirates
12.22. United Kingdom

13. Competitive Landscape
13.1. FPNV Positioning Matrix
13.1.1. Quadrants
13.1.2. Business Strategy
13.1.3. Product Satisfaction
13.2. Market Ranking Analysis, By Key Player
13.3. Market Share Analysis, By Key Player
13.4. Competitive Scenario
13.4.1. Merger & Acquisition
13.4.2. Agreement, Collaboration, & Partnership
13.4.3. New Product Launch & Enhancement
13.4.4. Investment & Funding
13.4.5. Award, Recognition, & Expansion

14. Company Usability Profiles
14.1. Abbott Laboratories
14.1.1. Business Overview
14.1.2. Key Executives
14.1.3. Product & Services
14.2. AbbVie Inc.
14.2.1. Business Overview
14.2.2. Key Executives
14.2.3. Product & Services
14.3. Actelion
14.3.1. Business Overview
14.3.2. Key Executives
14.3.3. Product & Services
14.4. Alexion Pharmaceuticals Inc.
14.4.1. Business Overview
14.4.2. Key Executives
14.4.3. Product & Services
14.5. Allergan plc
14.5.1. Business Overview
14.5.2. Key Executives
14.5.3. Product & Services
14.6. Amicus Therapeutics
14.6.1. Business Overview
14.6.2. Key Executives
14.6.3. Product & Services
14.7. BioMarin Pharmaceutical Inc.
14.7.1. Business Overview
14.7.2. Key Executives
14.7.3. Product & Services
14.8. CANBridge Pharmaceuticals
14.8.1. Business Overview
14.8.2. Key Executives
14.8.3. Product & Services
14.9. Clinigen Group
14.9.1. Business Overview
14.9.2. Key Executives
14.9.3. Product & Services
14.10. Generium
14.10.1. Business Overview
14.10.2. Key Executives
14.10.3. Product & Services
14.11. Horizon Pharma Public Limited Company
14.11.1. Business Overview
14.11.2. Key Executives
14.11.3. Product & Services
14.12. Intouch Pharmacy
14.12.1. Business Overview
14.12.2. Key Executives
14.12.3. Product & Services
14.13. Menarini
14.13.1. Business Overview
14.13.2. Key Executives
14.13.3. Product & Services
14.14. MLD Foundation
14.14.1. Business Overview
14.14.2. Key Executives
14.14.3. Product & Services
14.15. Pfizer Inc.
14.15.1. Business Overview
14.15.2. Key Executives
14.15.3. Product & Services
14.16. Protalix Biotherapeutics
14.16.1. Business Overview
14.16.2. Key Executives
14.16.3. Product & Services
14.17. Recordati Rare Diseases.
14.17.1. Business Overview
14.17.2. Key Executives
14.17.3. Product & Services
14.18. Sanofi S.A.
14.18.1. Business Overview
14.18.2. Key Executives
14.18.3. Product & Services
14.19. Shire Plc
14.19.1. Business Overview
14.19.2. Key Executives
14.19.3. Product & Services
14.20. Sigma Aldrich
14.20.1. Business Overview
14.20.2. Key Executives
14.20.3. Product & Services
14.21. Sigma-Tau Pharmaceuticals Inc.
14.21.1. Business Overview
14.21.2. Key Executives
14.21.3. Product & Services
14.22. Takeda Pharmaceutical Company Ltd
14.22.1. Business Overview
14.22.2. Key Executives
14.22.3. Product & Services
14.23. Teijin Pharma Ltd
14.23.1. Business Overview
14.23.2. Key Executives
14.23.3. Product & Services

15. Appendix
15.1. Discussion Guide
15.2. License & Pricing